open_targets.target_tractability

Python

In [1]:

import bedrock_bio as bb

rel = bb.load_table('open_targets.target_tractability')

df = rel.limit(5).pl()  # Polars
df = rel.limit(5).df()  # Pandas
df.head()

Out[1]:

	targetId	modality	category	value	version
0	ENSG00000146648	SM	Approved Drug	True	26.09
1	ENSG00000146648	SM	Advanced Clinical	False	26.09
2	ENSG00000146648	SM	Phase 1 Clinical	False	26.09
3	ENSG00000146648	SM	Structure with Ligand	True	26.09
4	ENSG00000146648	SM	High-Quality Ligand	True	26.09

R

In [1]:

library(bedrockbio)

lf <- load_table("open_targets.target_tractability")
df <- head(lf, 5) |> collect()

head(df)

Out[1]:

Sample output (5 rows)
   targetId        | modality | category              | value | version
   --------------- | -------- | --------------------- | ----- | -------
0  ENSG00000146648 | SM       | Approved Drug         | true  | 26.09
1  ENSG00000146648 | SM       | Advanced Clinical     | false | 26.09
2  ENSG00000146648 | SM       | Phase 1 Clinical      | false | 26.09
3  ENSG00000146648 | SM       | Structure with Ligand | true  | 26.09
4  ENSG00000146648 | SM       | High-Quality Ligand   | true  | 26.09

Description

Per-target tractability bucket assessments across small molecule, antibody, and other drug modalities [Target]

Partitions

Not partitioned.

Schema

Column	Type	Description
targetId	TEXT	Ensembl gene identifier of the assessed target [bioregistry:ensembl]
modality	TEXT	Drug modality the tractability assessment applies to (e.g. Small molecule, Antibody)
category	TEXT	Identifier of the tractability bucket assessed (e.g. clinical phase, structural evidence source)
value	BOOLEAN	Boolean outcome of the tractability bucket assessment
version	TEXT	Open Targets Platform release version (major.minor), e.g. 26.09. Added during ingest.