Skip to content
bedrock.bio

open_targets.evidence_crispr

import bedrock_bio as bb

rel = bb.load_table('open_targets.evidence_crispr')

df = rel.limit(5).pl()  # Polars
df = rel.limit(5).df()  # Pandas
df.head()
id targetFromSourceId diseaseFromSourceMappedId targetFromSource diseaseFromSource resourceScore literature datasourceId datatypeId diseaseCellLines qualityControls diseaseId targetId publicationDate evidenceDate score version
0 57240fdbe4c74449abe1b5ff3cf56974cf3fd4fb ENSG00000092531 EFO_0000182 SNAP23 hepatocellular carcinoma 44.799999 [38215750] crispr affected_pathway [{'id': 'SIDM01439', 'name': 'SNU-761', 'tissu... [] MONDO_0007256 ENSG00000092531 2024-01-11 2024-01-11 0.448 26.09
1 c3788688dcf92fbadaf7e592bbc5618a168a16c8 ENSG00000103356 EFO_0000182 EARS2 hepatocellular carcinoma 37.599998 [38215750] crispr affected_pathway [{'id': 'SIDM01439', 'name': 'SNU-761', 'tissu... [] MONDO_0007256 ENSG00000103356 2024-01-11 2024-01-11 0.415 26.09
2 f1cb6c9c24db1564da52354918896bb79851d1b0 ENSG00000105976 MONDO_0018177 MET glioblastoma 47.599998 [38215750] crispr affected_pathway [{'id': 'SIDM01421', 'name': 'U-343-MGa', 'tis... [] MONDO_0018177 ENSG00000105976 2024-01-11 2024-01-11 0.476 26.09
3 9fc0709f6481d544857331e71013197d457ea4cb ENSG00000122025 EFO_0000222 FLT3 acute myeloid leukemia 65.199997 [38215750] crispr affected_pathway [{'id': 'SIDM00437', 'name': 'MOLM-13', 'tissu... [] MONDO_0018874 ENSG00000122025 2024-01-11 2024-01-11 0.652 26.09
4 43498fd37c2294667514567a6a59aae8c3c532b8 ENSG00000038358 MONDO_0044925 EDC4 oral cavity carcinoma 42.900002 [38215750] crispr affected_pathway [{'id': 'SIDM00473', 'name': 'PE-CA-PJ15', 'ti... [] MONDO_0044925 ENSG00000038358 2024-01-11 2024-01-11 0.429 26.09

Description

Section titled “Description”

Disease-target evidence from unified analysis of whole-genome CRISPR/Cas9 screens from ProjectScore project [Target-Disease]

Partitions

Section titled “Partitions”

Not partitioned.

Schema

Section titled “Schema”
Column Type Description
id TEXT Identifer of the disease/target evidence
targetFromSourceId TEXT Target ID in resource of origin (accepted sources include Ensembl gene ID, Uniprot ID, gene symbol), only capital letters are accepted
diseaseFromSourceMappedId TEXT Mapped Open Targets disease identifier
targetFromSource TEXT Target name/synonym or non HGNC symbol in resource of origin
diseaseFromSource TEXT Disease label from the original source
resourceScore DOUBLE Score provided by datasource indicating strength of target-disease association
literature TEXT[] List of PubMed or preprint reference identifiers
datasourceId TEXT Identifer of the evidence source
datatypeId TEXT Type of the evidence
diseaseCellLines STRUCT(id TEXT, name TEXT, tissue TEXT, tissueId TEXT)[] Cancer cell lines used to generate evidence
qualityControls TEXT[] Evidence quality flags
diseaseId TEXT Open Targets disease identifier
targetId TEXT Open Targets target identifier
publicationDate TEXT Date of the earliest publication supporting the evidence
evidenceDate TEXT Earliest data for the evidence
score DOUBLE Score of the evidence reflecting the strength of the disease/target relationship
version TEXT Open Targets Platform release version (major.minor), e.g. 26.09. Added during ingest.