open_targets.mouse_phenotype

Python

In [1]:

import bedrock_bio as bb

rel = bb.load_table('open_targets.mouse_phenotype')

df = rel.limit(5).pl()  # Polars
df = rel.limit(5).df()  # Pandas
df.head()

Out[1]:

	targetInModel	targetInModelMgiId	targetInModelEnsemblId	targetFromSourceId	modelPhenotypeId	modelPhenotypeLabel	biologicalModels	modelPhenotypeClasses	version
0	1500009L16Rik	MGI:1917034	ENSMUSG00000087651	ENSG00000235162	MP:0002968	increased circulating alkaline phosphatase level	[{'allelicComposition': '1500009L16Rik<em1(IMP...	[{'id': 'MP:0005376', 'label': 'homeostasis/me...	26.09
1	1600014C10Rik	MGI:1919494	ENSMUSG00000054676	ENSG00000131943	MP:0006035	abnormal mitochondrial morphology	[{'allelicComposition': '1600014C10Rik<em1(IMP...	[{'id': 'MP:0005384', 'label': 'cellular pheno...	26.09
2	1600014C10Rik	MGI:1919494	ENSMUSG00000054676	ENSG00000131943	MP:0008493	alpha-synuclein inclusion body	[{'allelicComposition': '1600014C10Rik<em1(IMP...	[{'id': 'MP:0003631', 'label': 'nervous system...	26.09
3	1600014C10Rik	MGI:1919494	ENSMUSG00000054676	ENSG00000131943	MP:0010047	axonal spheroids	[{'allelicComposition': '1600014C10Rik<em1(IMP...	[{'id': 'MP:0003631', 'label': 'nervous system...	26.09
4	1700010I14Rik	MGI:1914181	ENSMUSG00000023873	ENSG00000112539	MP:0020451	decreased sperm progressive motility	[{'allelicComposition': '1700010I14Rik<em1Osb>...	[{'id': 'MP:0005389', 'label': 'reproductive s...	26.09

R

In [1]:

library(bedrockbio)

lf <- load_table("open_targets.mouse_phenotype")
df <- head(lf, 5) |> collect()

head(df)

Out[1]:

Sample output (5 rows, showing 7 of 9 columns)
   targetInModel | targetInModelMgiId | targetInModelEnsemblId | targetFromSourceId | modelPhenotypeId | modelPhenotypeLabel      | version
   ------------- | ------------------ | ---------------------- | ------------------ | ---------------- | ------------------------ | -------
0  1500009L16Rik | MGI:1917034        | ENSMUSG00000087651     | ENSG00000235162    | MP:0002968       | increased circulating a… | 26.09
1  1600014C10Rik | MGI:1919494        | ENSMUSG00000054676     | ENSG00000131943    | MP:0006035       | abnormal mitochondrial … | 26.09
2  1600014C10Rik | MGI:1919494        | ENSMUSG00000054676     | ENSG00000131943    | MP:0008493       | alpha-synuclein inclusi… | 26.09
3  1600014C10Rik | MGI:1919494        | ENSMUSG00000054676     | ENSG00000131943    | MP:0010047       | axonal spheroids         | 26.09
4  1700010I14Rik | MGI:1914181        | ENSMUSG00000023873     | ENSG00000112539    | MP:0020451       | decreased sperm progres… | 26.09

Description

Phenotypes of mouse models mapped to human targets [Target]

Partitions

Not partitioned.

Schema

Column	Type	Description
targetInModel	TEXT	Name of the target gene as represented in the mouse model
targetInModelMgiId	TEXT	Mouse Genome Informatics (MGI) identifier for the target gene in the model [bioregistry:mgi]
targetInModelEnsemblId	TEXT	Ensembl identifier for the target gene in the mouse model [bioregistry:ensembl]
targetFromSourceId	TEXT	Identifier for the human target as provided by the data source
modelPhenotypeId	TEXT	Identifier for the specific phenotype observed in the model [bioregistry:mp]
modelPhenotypeLabel	TEXT	Human-readable label describing the observed phenotype
biologicalModels	STRUCT(allelicComposition TEXT, geneticBackground TEXT, id TEXT, literature TEXT[])[]	Container for all biological model-related attributes.
modelPhenotypeClasses	STRUCT(id TEXT, label TEXT)[]	Container for phenotype class-related attributes
version	TEXT	Open Targets Platform release version (major.minor), e.g. 26.09. Added during ingest.