evidence_intogen

Identifier

open_targets.evidence_intogen

Description

Cancer-driver gene evidence based on the analysis of large-scale mutational data from IntOGen [Target-Disease]

Partitions

• release
  • '26.06'

Schema

Column	Type	Description
targetId	TEXT	Open Targets target identifier
id	TEXT	Identifer of the disease/target evidence
targetFromSourceId	TEXT	Target ID in resource of origin (accepted sources include Ensembl gene ID, Uniprot ID, gene symbol), only capital letters are accepted
diseaseFromSourceMappedId	TEXT	Mapped Open Targets disease identifier
datatypeId	TEXT	Type of the evidence
datasourceId	TEXT	Identifer of the evidence source
cohortId	TEXT	Identifier of the studied cohort
cohortShortName	TEXT	Short name of the studied cohort
cohortDescription	TEXT	Description of the studied cohort
significantDriverMethods	TEXT[]	Methods to detect cancer driver genes producing significant results
mutatedSamples	STRUCT(functionalConsequenceId TEXT, numberMutatedSamples BIGINT, numberSamplesTested BIGINT, numberSamplesWithMutationType BIGINT)[]	Samples with a given mutation tested
diseaseFromSource	TEXT	Disease label from the original source
resourceScore	DOUBLE	Score provided by datasource indicating strength of target-disease association
literature	TEXT[]	List of PubMed or preprint reference identifiers
qualityControls	TEXT[]	Evidence quality flags
diseaseId	TEXT	Open Targets disease identifier
publicationDate	TEXT	Date of the earliest publication supporting the evidence
evidenceDate	TEXT	Earliest data for the evidence
score	DOUBLE	Score of the evidence reflecting the strength of the disease/target relationship
directionOnTrait	TEXT	Predicted direction of effect on the trait
directionOnTarget	TEXT	Gain or loss of function effect of the evidence on the target resulting from genetic variants, pharmacological modulation, or other perturbations
release	TEXT	Partition column. Open Targets Platform release version (major.minor), e.g. 26.06. [Added during ingest.]