interaction

Identifier

open_targets.interaction

Description

Integration of molecular interactions reporting experimental or functional interactions between molecules represented as Platform targets.

This dataset contains pairwise interactions deposited in several databases capturing: physical interactions (e.g. IntAct), directional interactions (e.g. Signor), pathway relationships (e.g. Reactome) or functional interactions (e.g. STRINGdb) [Target]

Partitions

• release
  • '26.06'

Schema

Column	Type	Description
sourceDatabase	TEXT	Source database reporting the molecular interaction
targetA	TEXT	Open Targets target identifier of the first molecule (target A) in the interaction [bioregistry:ensembl]
intA	TEXT	Identifier for target A in source
intABiologicalRole	TEXT	Biological role of target A in the interaction
targetB	TEXT	Open Targets target identifier of the second molecule (target B) in the interaction [bioregistry:ensembl]
intB	TEXT	Identifier for target B in source
intBBiologicalRole	TEXT	Biological role of target B in the interaction
speciesA	STRUCT(mnemonic TEXT, scientificName TEXT, taxonId BIGINT)	Taxonomic annotation of target A
speciesB	STRUCT(mnemonic TEXT, scientificName TEXT, taxonId BIGINT)	Taxonomic annotation of target B
count	BIGINT	Number of interaction occurrences reported in the source databases
scoring	DOUBLE	Scoring or confidence value assigned to the interaction
release	TEXT	Partition column. Open Targets Platform release version (major.minor), e.g. 26.06. [Added during ingest.]