openfda_significant_adverse_drug_reactions

Identifier

open_targets.openfda_significant_adverse_drug_reactions

Description

Significant adverse drug reactions (ADRs) associated with drugs.

This dataset is based on the FDA’s Adverse Event Reporting System (FAERS) reporting post-marketing surveillance data and it’s filtered to include only reports submitted by health professionals.

The significance of a given drug-ADR is estimated using a Likelihood Ratio Test (LRT) using all reports associated with the given drug [Drug]

Partitions

• release
  • '26.06'

Schema

Column	Type	Description
chembl_id	TEXT	Unique identifier for the drug or clinical candidate
event	TEXT	Reported adverse drug reaction associated with the drug
count	BIGINT	Number of occurrences of the adverse event in the dataset
llr	DOUBLE	Log-likelihood ratio (LLR) measuring the strength of the association between the drug and the adverse event
critval	DOUBLE	Critical value used to determine statistical significance of the association
meddraCode	TEXT	Medical Dictionary for Regulatory Activities (MedDRA) code for the adverse drug reaction
release	TEXT	Partition column. Open Targets Platform release version (major.minor), e.g. 26.06. [Added during ingest.]