credible_set

Identifier

open_targets.credible_set

Description

95% credible sets for GWAS and molQTL studies.

Credible sets include all variants in the credible set as well as the fine-mapping method and statistics used to estimate the credible set [Genetics]

Partitions

• release
  • '26.06'

Schema

Column	Type	Description
studyLocusId	TEXT	Study-locus identifier for the credible set
studyId	TEXT	Identifier for the study which the credible set is derived
variantId	TEXT	The lead variant for the credible set, by posterior probability
chromosome	TEXT	Chromosome which the credible set is located
position	INT	Position of the lead variant for the credible set (GRCh38)
region	TEXT	Start and end positions of the region used for fine-mapping
beta	DOUBLE	Beta coefficient of the lead variant
zScore	DOUBLE	Z-score of the lead variant from the GWAS
pValueMantissa	FLOAT	Mantissa value of the lead variant P-value
pValueExponent	INT	Exponent value of the lead variant P-value
effectAlleleFrequencyFromSource	FLOAT	Allele frequency of the lead variant from the GWAS
standardError	DOUBLE	Standard error of the lead variant
subStudyDescription	TEXT	[Deprecated]
qualityControls	TEXT[]	Quality control flags for this credible set
finemappingMethod	TEXT	Method used for fine-mapping of credible set
credibleSetIndex	INT	Integer label for the order of credible sets from study-region
credibleSetlog10BF	DOUBLE	Log10 Bayes factor for the entire credible set
purityMeanR2	DOUBLE	Mean R-squared linkage disequilibrium for variants in the credible set
purityMinR2	DOUBLE	Minimum R-squared linkage disequilibrium for variants in the credible set
locusStart	INT	Start position of the region that was fine-mapped for this credible set
locusEnd	INT	End position of the region that was fine-mapped for this credible set
sampleSize	INT	Sample size of the study from which this credible set is derived
ldSet	STRUCT(tagVariantId TEXT, r2Overall DOUBLE)[]	Array of structs which denote the variants in LD with the credible set lead variant
locus	STRUCT(is95CredibleSet BOOLEAN, is99CredibleSet BOOLEAN, logBF DOUBLE, posteriorProbability DOUBLE, variantId TEXT, pValueMantissa FLOAT, pValueExponent INT, beta DOUBLE, standardError DOUBLE, r2Overall DOUBLE)[]	Array of structs which denote the variants within the credible set
confidence	TEXT	Description of how this credible set was derived in terms of data and fine-mapping method
studyType	TEXT	Descriptor for whether the credible set is derived from GWAS or molecular QTL
isTransQtl	BOOLEAN	Boolean for whether this credible set is a trans-pQTL or not
release	TEXT	Partition column. Open Targets Platform release version (major.minor), e.g. 26.06. [Added during ingest.]