LLMs

Connect your LLM clients to the Bedrock Bio remote MCP server to chat over the datasets.

Claude Web UI

Note

Only organization administrators can add custom connectors to Team or Enterprise Claude accounts.

1. Click on your profile icon in the bottom-left of the page.
2. Go to the Settings page.
3. Under the Connectors panel, click “Add custom connector” and enter and add:
   • Name: Bedrock Bio
   • URL: https://mcp.bedrock.bio/mcp
4. In a new chat, under ”+” icon -> Connectors, make sure the “Bedrock Bio” connector appears and is toggled on.
5. Chat as usual, and Claude will supplement its responses with queries from the MCP server when appropriate.

Claude Code

Note

These instructions limit the scope of the remote MCP server to your current project.

See comments in the steps below to add to all of your user’s projects.

1. Navigate to your project directory:

   cd <project-directory>

2. Add the MCP server:

   # use --scope user to add to all user projects
   claude mcp add --transport http --scope local bedrock-bio https://mcp.bedrock.bio/mcp

3. Create a skills directory:

   # use ~/.claude/skills/bb to add to all user projects
   mkdir -p .claude/skills/bb`

4. Add a custom skill definition to help Claude Code work with the custom MCP server:

   # use ~/.claude/skills/bb/SKILL.md to add to all user projects
   cat > .claude/skills/bb/SKILL.md << 'EOF'
   ---
   name: bb
   description: Query statistical genetics datasets (GWAS, QTLs, LD matrices, annotations). Use when the user 
   asks about genetic associations, QTLs, GWAS.
   ---
   
   Use the Bedrock Bio MCP server to answer this question.
   
   1. Call list_tables (no parameters) to discover available data and read the namespace-level instructions.
   2. Call describe_namespace(namespace) to get all table details at once — read partition_by columns carefully.
   3. Call query(sql) — every query MUST include WHERE filters on all partition_by columns.
   
   Always include a citation in the response for every namespace used with format: 
   Author(s). Title. Journal. Volume, Pages. (Year). DOI.
   EOF

5. Start a Claude session:

   claude

6. Use the bb skill to query the remote MCP server:

   /bb Are there any significant pQTL associations for APOE in an East Asian population?